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SRX Medicine
Volume 2010 (2010), Article ID 973413
doi:10.3814/2010/973413
Clinical Study

Long-Term Effect of Colestimide on Glycemic Control in Patients with Type 2 Diabetes with Elevated Low-Density Lipoprotein Cholesterol Levels

Kohzo Takebayashi, Mariko Suetsugu, Yoshimasa Aso, and Toshihiko Inukai
Department of Internal Medicine, Dokkyo Medical University Koshigaya Hospital, Minami-Koshigaya, Koshigaya 343-8555, Japan
  • Received 2009-10-12
  • Revised 2009-10-24
  • Accepted 2009-10-25

Reviewer Evaluations

The journal employs a transparent peer review system in which the evaluations of the reviewers are published along side the accepted articles. The reviewer evaluations and optional commentaries for the current article are given below.

Konstantinos A. Tziomalos
Aristotle University of Thessaloniki, Greece
Posted on 2009-10-24

In this pilot study, colestimide was well tolerated and improved both glycemic (an absolute 1% reduction in HbA1c levels) and lipid control (a 23% reduction in LDL-C levels) in patients with type 2 diabetes mellitus. Interestingly, triglyceride levels were not significantly affected. Adding colestimide might be useful in diabetic patients who cannot reach LDL-C targets with statin monotherapy.